Methylene Blue Benefits and Uses

by Sara Banta | Apr 24, 2024 | AHP News, brain health supplements, Supplements

Methylene blue has become a highly searched supplement for a number of reasons. It is a versatile compound that has been studied for various potential benefits. First developed in 1891 to stain and devitalize certain microbes, it was also one of the first chemotherapeutic medications tested in humans to treat malaria.

Methylene blue is known as a diamino phenothiazine, with a low redox potential which allows it to facilitate electron transport in the mitochondria. This action increases ATP production while reducing mitochondrial superoxide production.

Methylene Blue Benefits

Some of the researched potential benefits of methylene blue include:

Antioxidant Properties: Methylene blue has antioxidant properties, meaning it can help combat oxidative stress in the body. Oxidative stress can be linked to various health issues, including chronic diseases.

Neuroprotective Effects: Research suggests that methylene blue may have neuroprotective effects. It has been investigated for its potential in treating neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease.

Methylene blue serves as an electron carrier, demonstrating efficacy against conditions like malaria and methemoglobinemia.

Particularly beneficial in cytotoxic scenarios within the brain, it stimulates cellular oxygen consumption and reduces anaerobic glycolysis. Through its electron carrier role, methylene blue can diminish the generation of reactive oxygen species (ROS), providing cellular protection against challenges like glutamate blockage.

It also mitigates the decline in mitochondrial membrane potential, and shields against IAA neurotoxicity, showcasing a range of advantageous effects. These properties hold significance for conditions such as Alzheimer’s disease, Parkinson’s disease, and stroke.

Comparative studies with antipsychotic drugs like phenothiazine reveal that while methylene blue shares neuroprotective effects, its mechanism differs. Present research indicates that methylene blue acts as a mitochondria-specific antioxidant, distinct from free radical scavengers like phenothiazine, which operate independently of the mitochondria.

Beyond neurodegenerative conditions, methylene blue exhibits the potential to prevent and manage brain damage associated with tumors. Alkylating agents like ifosfamide, used in the treatment of certain solid tumors, can induce brain damage. Methylene blue’s role in the oxidation of NADH and restoration of mitochondrial enzymes appears to contribute to mitigating this damage, although the exact mechanism is not fully elucidated.

Enhancement of Mitochondrial Function: Methylene blue is known to interact with mitochondria, the energy-producing organelles in cells. Some studies suggest that it may enhance mitochondrial function and improve cellular energy production. It can suppress mitochondrial dysfunction, subsequent oxidative damage, and ATP decline. Furthermore, methylene blue is both water and organic soluble, making it highly permeable in cell membranes; it enters the cells at the level of mitochondria, nucleus, and lysosomes easily.

Antimicrobial Properties: Methylene blue exhibits antimicrobial properties and has been explored for its potential in treating infections. It has shown effectiveness against various bacteria, viruses, and fungi.

Cognitive Enhancement: There is some evidence to suggest that methylene blue may have cognitive-enhancing effects. It has been studied for its potential to improve memory and cognitive function.

Treatment for Methemoglobinemia: Methylene blue is used as a medical treatment for methemoglobinemia, a condition where there is an abnormal increase in the amount of methemoglobin in the blood. Methemoglobin is a form of hemoglobin that cannot bind oxygen effectively.

Antidepressant Properties: Some research indicates that methylene blue may have antidepressant effects as it may increase serotonin. It has been explored as an adjunctive treatment for depression.

Increase Nitric Oxide: Methylene blue may increase nitric oxide, and nitric oxide acts as a natural vasodilator, relaxing blood vessels and promoting improved blood flow.

Wound Healing: Methylene blue has been studied for its potential role in wound healing. It may help in reducing inflammation and promoting tissue repair.

Skin Improvement: Oxidative stress is the major cause of aging skin including wrinkles, pigmentation, and weakened wound healing. Methylene blue is a potent reactive oxygen species (ROS) scavenger and can stimulate skin fibroblast proliferation and delay cellular senescence. Furthermore, methylene blue may help collagen and elastin formation in the skin without the skin irritation that comes with retinol. It has been shown to reduce biomarkers of physiological aging in skin cells.

Treatment for Cyanide Poisoning: Methylene blue is used as an antidote for cyanide poisoning. It can help in detoxifying cyanide by converting it into a less toxic form.

Treatment for Brain Injury: The brain is very sensitive to oxygen and glucose deprivation due to its high energy demands; methylene blue has been shown to be neuroprotective in several injury models, due to its antioxidant capacity and ability to facilitate alternative mitochondrial transfer. It was shown to help with inflammation as well.

Why Accelerated Methylene Blue

Accelerated Methylene Blue is made with John Ellis Distilled Water and filtered through the GRANDER® water system. The ingredients are 100% pure.

John Ellis Distilled Water: Using patented distillers, the bond angle remains above 108 degrees, which is known to kill toxins in our food supply by eliminating the effect of pathogens. The hydrogen bond angle remains 10 degrees greater than ordinary water. This is the only water in the world that can kill pathogens using frothing, concentrated heat, and ultraviolet energy. This is important because low-energy water, like regular water, steals energy from your food to reach equilibrium. This affects your immune system, as it needs that precious energy to fight disease.

The GRANDER® Water System: Living water creates a natural energy field that can offset the adverse effects of unhealthy electromagnetic fields.
GRANDER® brings to water the beneficial energy and information it needs to rebuild its optimal inner qualities.

Unlike filters, whose benefits are derived from removing contaminants from the water, the GRANDER® products improve water quality by improving the water’s internal structure and enhancing its energetic quality. As a result of this treatment, the water is capable of restoring its inner qualities, is more available to living systems, and exhibits enhanced stability and self-cleaning properties. Dependence upon detergents and chemicals to manage water quality may often be reduced. Most importantly, traces of negative information that are left behind by pollutants are reversed, as the water rebuilds and renews its internal energetic qualities

Water has valuable biological properties wherever it can be found in its original form and can follow its natural course. Water is a bubbling source of vitality and vital force, yet it loses its energy and power when squeezed into tubes and pumped into pipes over long distances to be delivered to our homes. The GRANDER® Water Revitalization units return water to its original structure – with all the various positive effects for humans and all living things.

Sara Banta
Accelerated Health Products | + posts

Sara Banta is a Stanford University Graduate with a Degree in Economics and Psychology, and a certified Natural Supplement Expert & Graduate of the Institute for Integrative Nutrition. Sara is the Founder of Accelerated Health Products and host of the health & wellness podcast, Accelerated Health Radio.

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Hi, I’m Sara Banta!
I’m a certified natural supplement expert, podcaster, Health Coach, and natural wellness expert. Each week I publish articles on the latest in cutting-edge health supplements and natural health solutions. I also interview leading experts across a wide range of health topics to transform your body, mind & spirit. I’m also the Founder of Accelerated Health Products. Join my mailing list and receive 10% off your first order.